what we do

We are working to address global challenges in energy, sustainability and infectious disease by engineering microbes to synthesize fuels, electricity and materials, and by deciphering microbial mechanisms of antibiotic resistance.

Our approach blends microbial physiology, genomics technologies, and computational biology to predict and modify microbial behaviors. Our work spans the disciplines of synthetic biology, systems biology and microbiology.

Our vision. In 50 years, we believe more than 50% of our energy and consumer materials will be synthesized through renewable biological processes. Infectious diseases will be controlled globally through rapid drug design technologies, helping us to stay ahead of emerging diseases and drug resistant microbes.


software and tools

the M3D database

A free resource for downloading, viewing and analyzing Affymetrix expression profiles. M3D includes compendia for multiple organisms
including E. coli, Shewanella & yeast.
access the database >>

the CLR algorithm
Maps regulatory interactions between transcription factors and their targets using a compendium of gene expression profiles.
download >>

1/1/08
Tim Gardner takes Leave from BU to direct Computational Biology at Amyris Biotechnologies

10/18/07
Gardner Lab is featured in Boston University's Research 2007 magazine

10/11/07
M3D Database is published in Nucleic Acids Research.

9/5/07
CLR version 1.2 released. Click to download.

8/28/07
M3D Database updated with structured metadata for all experiments

5/10/07
Presentations from the Clean Energy symposium at Boston University are online

1/22/07
CLR algorithm is highlighted in Technology Review magazine

1/10/07
Our latest article on regulatory network mapping appears in PLoS Biology

more news >>